Ligandrol (also known as LGD-4033, or LGD, or LGD4033) is touted by Bodybuilders as being a healthier replacement to the most powerful muscle building oral steroids Dianabol (Dbol or D-bol) and Anadrol (Drol).*
LGD-4033 binds to the androgen receptor of muscle and bone selectively, exhibiting similar effects as testosterone*, with only partial agonist activity on the prostate. It was developed as a way to treat diseases or conditions associated with muscle and bone deterioration. The advantage a SARM like LGD has over testosterone is the difference in activity it has on the body outside of muscle and bone.*
We are excited for more research to be done on LGD-4033 because this could be the future of hormone replacement therapy and the end of muscle wasting.* However, until it is prescribed by a doctor for personal use it is strictly prohibited for human consumption and it is for research purposes only. We hope that someday steroids can be replaced with these SARMS and prescribed by Doctors giving all the benefits of Steroids with reduced or no side effects. Until prescribed by a doctor it cannot be ruled out that this compound will cause in humans death and serious bodily injury.
Anecdotal evidence shows that the human dosage may be around 10mg (5mg twice per day), although since LGD is in the class of drugs of SARMS and too powerful to sell as a supplement for human consumption, no recommended dosage has been approved. Once LGD passes all its FDA testing (approximately 10 years), a recommended dosage will be published and Doctors will be able to prescribe a dosage unique to the individual based on the guidelines.
Anecdotal evidence shows that human use of LGD-4033 will result in reduction of natural testosterone production. This is because the body thinks the compound is testosterone and therefore produces less. Therefore anyone who undergoes research with LGD should look into PCT Post Cycle Therapy to regenerate natural testosterone production and prevent a hormonal rebound of hormones such as estrogen.